Search results for " ultrasonic stimulation"

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Direct activation of zebrafish neurons by ultrasonic stimulation revealed by whole CNS calcium imaging

2020

Abstract Objective. Ultrasounds (US) use in neural engineering is so far mainly limited to ablation through high intensity focused ultrasound, but interesting preliminary results show that low intensity low frequency ultrasound could be used instead to modulate neural activity. However, the extent of this modulatory ability of US is still unclear, as in in vivo studies it is hard to disentangle the contribution to neural responses of direct activation of the neuron by US stimulation and indirect activation due either to sensory response to mechanical stimulation associated to US, or to propagation of activity from neighboring areas. Here, we aim to show how to separate the three effects and…

Ultrasonic Therapy0206 medical engineeringBiomedical EngineeringCalcium imagingStimulationSensory systembrain-stimulation02 engineering and technologysystem03 medical and health sciencesCellular and Molecular NeuroscienceUltrasounds0302 clinical medicineCalcium imagingmedicineAnimalsZebrafishZebrafishNeuronscalcium imaging ultrasonic stimulation ultrasound zebrafishSensory stimulation therapybiologyCalcium imaging; Neuromodulation; Ultrasounds; ZebrafishNeuromodulationneuromodulation; zebrafish; ultrasounds; calcium imagingtranscranial focused ultrasoundNeural engineeringbiology.organism_classification020601 biomedical engineeringNeuromodulation (medicine)cellular resolutionmedicine.anatomical_structureLarvaCalciumNeuronNeuroscience030217 neurology & neurosurgeryneurostimulation
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